Endocrine Abstracts

Objective: Normocalcemic primary hyperparathyroidism (PHPT) is a phenotype of PHPT characterized by normal serum calcium and persistently increased parathyroid hormone (PTH) after exclusion of secondary causes of PTH elevation.The aim: of this study was to investigate the capability of the short test with active metabolites of vitamin D for differential diagnosis between normocalcemic PHPT and secondary hyperparathyroidism (SHPT) for inpatient treatment....

Background: Primary hyperparathyroidism (PHPT) can present with not only classic complications like bone and kidney pathology but also with different metabolic disorders and cardiovascular diseases. The prevalence of diabetes mellitus type 2 (DM2) in patients with PHPT is higher than in general population but the mechanism of carbohydrate metabolism alteration in PHPT remains unclear.Aim: The aim of this study is to estimate parameters associated with im...

Introduction: Primary hyperparathyroidism (PHPT) is commonly the most early manifestation of multiple endocrine neoplasia syndrome type 1 (MEN1), but it can also occur in young patients without any inherited disorders. The aim of our study was to compare the clinical characteristics of PHPT in young patients with MEN1 syndrome and with sporadic disease.Patients and Methods: The study included 72 patients with MEN-1 associated PHPT and 168 patients with s...

Introduction: Chronic hypoparathyroidism is a rare disease, which usually treated with active forms of vitamin D and oral calcium. Supplementation with native vitamin D can be useful both for achieving "non-skeletal" effects of vitamin D and for a more stable serum calcium profile.Aim: The aim of this study was to estimate the daily serum calcium and 24-hour urine calcium levels in patients with chronic hypoparathyroidism depending on different 2...